A B C D E F G H I J K L M N O P Q R S T U V W X Y Z All
Jeong, Sung-Hun
- Changes in Chemical Structure of Iopamidol Contrast Agents According to Radiation and Environmental Conditions
Authors
1 Doctoral Student, Dept. of Health Care, Hanseo University, KR
2 Professor, Dept. of Health Care, Hanseo University, KR
3 Doctor, Dept. of Radiology, Seosan Jungang General Hospital, KR
Source
Medico-Legal Update, Vol 20, No 1 (2020), Pagination: 1511-1515Abstract
Background: To prevent contrast agent’s side effects, it is important to provide accurate information about the contrast agent and fulfill the duty of explaining the medication, experience of side effects, and medical history. However, the incidence of safety accidents associated with contrast agents is continuously increasing. Therefore, the objective of this study was to prepare an improvement plan for problems derived by analyzing changes in chemical structure of contrast medium according to radiation and external environment. Method: The chemical structure of the standard sample was analyzed using Nuclear Magnetic Resonance Spectroscopy (NMR) in P contrast agent of Iopamidol preparations used in Korean medical institutions. Samples were obtained by irradiation under 3Gy and 5Gy conditions according to the Photon 10MV, Electron 20MeV condition and the radiation dose according to the radiation and environmental conditions. Contrast agent samples after opening and sealed but expired samples were also obtained. These samples were analyzed and chemical shift values in the 1H-NMR spectrum using NMR analysis were compared. Findings: 1H-NMR analysis results of P contrast medium irradiated with Photon 10MV and 5Gy and sealed but expired P contrast medium samples showed no change in chemical shift. However, there were changes in chemical shift value in P standard sample, showing triple peaks in 1.1-1.2ppm range. In addition, the sample irradiated by Electron 20MeV and 3Gy showed double peaks. The sample irradiated by Electron 20MeV and 3Gy condition showed a single peak in the 3.0-3.5ppm region, demonstrating a change in chemical shift value. In the 1.0-1.4ppm region, P contrast medium standard samples showed triple peaks and opened contrast medium samples showed double peaks in the middle peak among the triplet, demonstrating changes in chemical shift value. Improvements: Changes in chemical structure of contrast agent were observed in contrast medium after electron irradiation and in contrast medium after opening. In this regard, guidelines for the administration of contrast medium should be prepared as soon as possible so that consumers could have accurate information and their right of choice.Keywords
Contrast Agent, Iopamidol, Chemical Structure, Radiation, NMR, Chemical Shift.
- Actual Pressure Ulcer Awareness of a Person in Charge of Pressure Ulcer Management
Authors
1 Dept. of Health Care, Hanseo University, 46, Hanseo 1-ro, Haemi-myeon, Seosan-si, Chungcheongnam-do, KP
2 Dept. of Radiology, Seosan Jungang General Hospital, Suseoksanupro, Chungcheongnam-do, KP
Source
Medico-Legal Update, Vol 20, No 1 (2020), Pagination: 1822-1826Abstract
Background/Objectives: The aging population due to increases of average life expectancy elderly population is perceived a serious problem in the medical sector. The objective of this study was to determine the degree of awareness of pressure ulcer in nurses in charge of pressure ulcer management in medical institutions and to provide basic data for setting guidelines.
Method/Statistical Analysis:A survey and analysis were conducted on 40 nurses in charge of nursing care at a nursing hospital. The survey tool was developed by quoting a pressure ulcer prevention management tool developed by Moore and Price. The survey was conducted in a face-to-face manner, explaining the purpose of the study directly. A total of five questions are recognized as pressure ulcer management, and the reliability is Cronbach’s α = .785 and consisted of a five-point Likert scale. The general characteristics are gender, age, work experience, Education, and hospital size of nursing hospital, with total five questions and reliability being Cronbach’s α = .654.
Findings: “How much do you know about the pressure ulcer?” showed the highest ‘Yes’ of 30%. In the pressure ulcer management knowledge section, “Do you know about changing your bed posture at least every two hours?” showed the highest ‘very yes’ of 82.5%. “Do you know the standard of management when a pressure ulcer occurs?” showed 45.0% of ‘Yes’ and “Do you know the factors involved in the pressure ulcer?” with 47.5%. “Do you know about the relationship between humidity and temperature among the factors involved in the pressure ulcer?” showed 57.5% (23).
Improvements/Applications: The results of this study show the degree of pressure ulcer management by nursing hospital nurses in charge of the pressure ulcer management. Knowledge of the pressure ulcers was high, but low awareness of the factors involved in the management standards emerged. It is expected that this data will be used as basic data for setting up education and management measures for the management of the pressure ulcers in the future.